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Accelerating Bipolar
Disorder Science

We are forging research pathways to lift the ceiling on scientific understanding and to create new interventions so that everyone with bipolar disorder can thrive.

Focusing science
on the greatest impact
for people.

Current research, treatment, and care for bipolar disorder lacks scientific precision of the disorder and its diversity. We aim to change that. 

Four Interconnected Programs, Zero Silos

Our mission is to accelerate scientific understanding of bipolar disorder and advance clinical care. Our Collaboration Projects provide BD² teams across programs with additional funding to promote data and resource sharing, as well as accelerate new findings.

Integrated Network

Bridge Insight With Precision Psychiatry

Integrated Network

Bridge Insight With Precision Psychiatry

Activate a collaborative infrastructure between clinical settings and a longitudinal research study to translate real-time findings into improvements in care. 
Brigham and Women's Hospital-McLean Hospital 
Johns Hopkins University
Mass General Brigham-McLean
Mayo Clinic
Ottawa Hospital Research Institute
The Feinstein Institutes for Medical Research
The University of Texas at Austin
The University of Texas Health Science Center at Houston
University of California, Los Angeles
University of California San Diego
University of Cincinnati/Lindner Center of HOPE
University of Michigan
Depression and Bipolar Support Alliance (DBSA)
Indoc Research
Mayo Clinic Biobank

Discovery Research

Discover the Biological Pathways

Discovery Research

Discover the Biological Pathways

Improve the scientific understanding of the biological mechanisms of bipolar disorder. 
Columbia University
KTH Royal Institute of Technology
Massachusetts General Hospital
Mass General Brigham
New York Genome Center
New York University
Northwestern University
Princeton
Rutgers University
Stanford University
Swinburne University
The Broad Institute of MIT and Harvard
University College, London
University of California, Berkeley
University of Oxford
University of Texas Austin
Wyss Institute at Harvard University
Yale University

Brain Omics Platform

Understand the Differences in the Brain

Brain Omics Platform

Understand the Differences in the Brain

Assess the transcriptomic, epigenetic, and proteomic characteristics of brain tissue derived from people with bipolar disorder. 
Icahn School of Medicine at Mount Sinai
University of Pittsburgh
California Institute of Technology

Genetics Platform

Uncover the Genetic Contributions

Genetics Platform

Uncover the Genetic Contributions

Perform genetic sequencing on a large, diverse population of people with bipolar disorder to contribute to the genetic database.
The Broad Institute of MIT and Harvard
University of California, Los Angeles
New York Genome Center

Who We Are

Our comprehensive, hypothesis-driven approach breaks down barriers between innovation, scientific findings, and clinical care.

News & Updates

Cultivating the power of collaboration.

BD2 is invested in the talent of our people and partners, fostering team development and connection across the network.

A message from our Managing Director

"The wonder of science is that while we can’t know where new discovery will come from, we can stack the deck in our favor and aim it towards the greatest impact for people."

Cara Altimus, PhD, Managing Director 

Engage &
Connect With
Us Today

Join us in achieving the vision of a world where all people with bipolar disorder thrive.

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Apply for Funding

Review current and past RFA opportunities.