BD² Updates
BD² Seeks Additional Clinic Sites for Multidisciplinary Initiative to Advance Understanding of Bipolar Disorder
Highlights: Expanding Existing Infrastructure: The BD² Integrated Network currently spans 11 clinical institutions across the U.S. and Canada, and is looking to add more sites. New Funding Announced: BD² is launching its third round of funding for new sites in its Integrated Network. Proposals are open to public, private, non-profit, and for-profit organizations in the …
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BD² Awards over $13 Million in Grants to Understand the Mechanisms of Mood State Switching in Bipolar Disorder and Announces New Funding Available
Highlights: Understanding Mood State Switching: Three new BD² Discovery Research teams will explore how external risk factors trigger manic or depressive episodes. New Insights: Research led by scientists and clinicians at Harvard Medical School, Johns Hopkins University, and Stanford University will offer new insights and potential treatments for people with bipolar disorder. New Funding Announced: …
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BD² Launches Data Science Fellowship for Early Career Scientists
Highlights: BD² plans to award eight new data science fellowships for early career investigators to advance bipolar disorder research. Each fellow will receive up to $250,000 over two years to drive collaborative research and support professional development. Fellows will work with BD² teams to uncover new scientific breakthroughs by analyzing the novel datasets collected by …
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Inside a Megadonor-Backed Funder’s Fight to Treat Bipolar Disorder
Inside Philanthropy highlights BD²’s progress since its 2022 launch, from expanding the field of bipolar disorder research and bringing new funders into the effort to connecting more than 350 researchers and clinicians and releasing the first public dataset from the BD² Integrated Network Longitudinal Cohort Study. The article underscores BD²’s collaborative, people-centered model for accelerating …
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BD² Releases Largest Multi‑Modal Psychiatric Dataset to Accelerate Breakthroughs in Bipolar Disorder
Highlights: Historic Scale: Data from 615 participants across initial six sites, forming the most comprehensive multimodal dataset ever created for a psychiatric condition. Integrated Modalities: Includes clinical assessments, MRI neuroimaging, blood-based biomarkers, and continuous wearable sensor data. Designed for Impact: Embedded within a Learning Health Network to rapidly translate discoveries into improved patient care. Open …
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Rethinking the Research Model: Women’s Health and the Future of Bipolar Science
On International Day of Women and Girls in Science, BD² is spotlighting the women advancing research and care for people living with bipolar disorder, and the work still needed to ensure women’s mental health is fully understood, represented, and prioritized in science. In a new roundtable discussion, Emily Baxi, PhD, Program Director of the BD² …
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2025 Milestone Report: Advancing a Future Where People with Bipolar Disorder Thrive
BD² closes 2025 with powerful momentum across our global research community. This year, we surpassed 1,000 participants enrolled, invested $100M+ across programs, and strengthened collaboration among 350+ scientists and clinicians working across 50+ institutions worldwide. The 2025 Milestone Report highlights major advances in clinical research, discovery science, genetics, and brain omics—along with new tools, partnerships, …
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BD² Awards $18 Million in Grants to Advance Research on the Biology of Bipolar Disorder
Washington, DC –Today, BD², or Breakthrough Discoveries for thriving with Bipolar Disorder, announced its third round of Discovery Research grants, totaling nearly $18 million – expanding a comprehensive global effort to examine the key mechanisms of bipolar disorder. Multidisciplinary teams of scientists and clinicians include leads from the Icahn School of Medicine at Mount …
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