BD² Integrated Network
A collaborative model that will improve care, interventions,
and outcomes for people with bipolar disorder.
Our approach combines the power of discovery with accelerated translation of findings to care by generating data collected in real-world clinical settings alongside a comprehensive longitudinal research study.
The Model
Recognizing an urgent need to drive progress in bipolar disorder research and care, BD² is bringing together an unprecedented depth of information from people with bipolar disorder to effectively lift the ceiling on current scientific understanding, create new treatment options, and drive a path towards wellness.
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Our Network
By learning more about participants’ daily lives and connecting them with clinicians and researchers who share data across sites, we are accelerating what we can learn about the biology of bipolar disorder, determining biologically defined subtypes, and providing a scientific basis for new, targeted treatments. Our clinical sites comprise 10 institutions with proven track records of excellence in bipolar disorder treatment.
Study Design
Our model interweaves a longitudinal cohort study, engaging people with bipolar disorder and their caregivers with a learning health network. The result is an unprecedented system that supports continual advancement in the understanding of bipolar disorder along with improvements in care.
Our Approach
The BD² Integrated Network works to improve the health and well-being of people living with bipolar disorder by engaging a network of collaborating investigators and clinicians to:
- implement and inform data-driven improvements in care
- build an unprecedented data ecosystem comprised of longitudinal clinical and biological data
- generate novel insights that will drive innovative approaches to bipolar disorder interventions and treatments
Project Outcomes
Today, it is estimated that it takes an average of 17 years to translate a scientific discovery to meaningful interventions for people with bipolar disorder.
The BD² Integrated Network aims to collapse that timeline so individuals participating in the network can benefit from better care, today. And more broadly, the network will be able to develop improved care guidelines for all.
Who’s Involved
The network consolidates the expertise of bipolar disorder clinicians and researchers into a collaborative initiative that will advance clinical care and lead to better outcomes for those living with bipolar disorder.
Each site has the capacity for significant participant enrollment in the longitudinal study and demonstrates a commitment to BD²’s mission of equitable healthcare and meaningful ethnic and racial representation in clinical trials and research studies alongside proven track records of contribution to multi-site initiatives and longitudinal studies.
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Johns Hopkins University
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Mass General Brigham-McLean
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Mayo Clinic
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The Feinstein Institutes for Medical Research
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The University of Texas at Austin
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The University of Texas Health Science Center at Houston
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University of California Los Angeles
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University of California San Diego
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University of Cincinnati/Lindner Center of HOPE
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University of Michigan
Key Partners
BD² has partnered with institutions and companies that bring together data, samples, processes, and analysis for the Integrated Network. Their tools and expertise are essential to a functional model.
Explore Our Work
Learn how BD² will close a fundamental gap in understanding the genetic and biological mechanisms of bipolar disorder.